Chapter 9 · 13 min

Maps, Measurements, and Experiments

Chapter 9 of How the Brain Works: Maps, Measurements, and Experiments.

Watch the complete chapter ↗

Visual credits

11 sources

Sources and credits for imagery used in this film, including material incorporated into explanatory animations.

  • Yao 2023 Figure 2a, Pallium-Glut similarity embedding

    Z. Yao, C. T. J. van Velthoven, M. Kunst and coauthors

    Incorporated into an explanatory animation; presentation may include cropping, labels and overlays.

  • Yao 2023 Figure 2b, six Pallium-Glut coronal sections

    Z. Yao, C. T. J. van Velthoven, M. Kunst and coauthors

    Incorporated into an explanatory animation; presentation may include cropping, labels and overlays.

  • Dorkenwald 2024 Figure 1e, annotated polyadic synapse

    S. Dorkenwald, A. Matsliah, A. R. Sterling and coauthors / FlyWire Consortium

    Incorporated into an explanatory animation; presentation may include cropping, labels and overlays.

  • Standing female Drosophila melanogaster

    Hannah Davis

    Incorporated into an explanatory animation; presentation may include cropping, labels and overlays.

    Standing female Drosophila melanogaster — Hannah Davis. CC BY-SA 4.0. https://commons.wikimedia.org/wiki/File:Standing_female_Drosophila_melanogaster.jpg

  • Dorkenwald 2024 Figure 1a, whole-brain reconstruction

    S. Dorkenwald, A. Matsliah, A. R. Sterling and coauthors / FlyWire Consortium

    Incorporated into an explanatory animation; presentation may include cropping, labels and overlays.

  • MICrONS 2025 Figure 4a, mouse and sampled-volume subregion

    The MICrONS Consortium; mouse drawing adapted from Mahalingam et al.

    Incorporated into an explanatory animation; presentation may include cropping, labels and overlays.

  • MICrONS Explorer synaptic-connectivity illustration

    MICrONS Consortium / MICrONS Explorer

    Incorporated into an explanatory animation; presentation may include cropping, labels and overlays.

  • Video demonstration of the Neuroglancer interface for the H01 dataset (Movie S1)

    Alexander Shapson-Coe

    Video demonstration of the Neuroglancer interface for the H01 dataset (Movie S1) — Alexander Shapson-Coe. Zenodo record 10875298. CC BY 4.0. https://doi.org/10.5281/zenodo.10875298

  • Shiu et al. 2024 title and author crop

    P. K. Shiu, G. R. Sterne, N. Spiller and coauthors

    Incorporated into an explanatory animation; presentation may include cropping, labels and overlays.

    Shiu et al. 2024 title and author crop — P. K. Shiu, G. R. Sterne, N. Spiller and coauthors. CC BY 4.0. https://www.nature.com/articles/s41586-024-07763-9

  • Shiu 2024 Figure 2c, complete confusion matrix

    P. K. Shiu, G. R. Sterne, N. Spiller and coauthors

    Figure or page excerpt cropped from the source publication.

  • Randi 2023 Figure 3c, measured versus predicted responses

    F. Randi, A. Sharma, S. Dvali and coauthors

    Incorporated into an explanatory animation; presentation may include cropping, labels and overlays.

Research references

Selected sources from the episode’s research and scientific figures.

  1. Siletti article ↗
  2. Yao article ↗
  3. Article ↗
  4. Shiu Nature paper ↗
  5. MICrONS resource paper ↗
  6. Zhuokun Ding et al., Functional connectomics reveals general wiring rule in mouse visual cortex ↗
  7. Lappalainen et al., Connectome-constrained networks predict neural activity across the fly visual system, Nature, 11 September 2024 ↗
  8. Wang et al., Foundation model of neural activity predicts response to new stimulus types, Nature, 9 April 2025 ↗
  9. 8 April 2026 author correction ↗
  10. Cubic Millimeter Explorer ↗
  11. release page ↗
  12. Explorer terms ↗
  13. FlyWire media page ↗
  14. The FlyWire Connectome ↗
  15. MICrONS Allen press video ↗
  16. MICrONS Neuroglancer tutorial ↗
  17. Male-CNS gallery ↗
  18. H01 Zenodo Movie S1 ↗
  19. Stanford digital-twin press story ↗
  20. Baylor NEURD press story ↗
  21. Tour a Fly Brain in Stunning Detail ↗
  22. Male-CNS portal ↗
  23. final PubMed record ↗
  24. Google's publication index ↗
  25. Allen dataset-specific terms ↗
  26. Siletti published record ↗
  27. original paper PDF ↗
  28. H01 Google release blog ↗
  29. Allen news article ↗
  30. Article ↗
  31. Final article ↗
  32. Zhiwei Ding, Dat Tran and colleagues, Functional bipartite invariance in mouse primary visual cortex receptive fields ↗
  33. 10.1098/rstb.1986.0056 ↗
  34. primary-paper archive at WormAtlas ↗
  35. OpenWorm's dataset provenance ↗
  36. Neural signal propagation atlas of Caenorhabditis elegans ↗
  37. From the connectome to brain function ↗
  38. accessible primary-paper copy ↗
  39. Could a Neuroscientist Understand a Microprocessor? ↗
  40. Creamer, Leifer and Pillow, Bridging the gap between the connectome and whole-brain activity in C. elegans ↗
  41. author code repository ↗
  42. Princeton functional-connectivity explorer ↗
  43. 10.7554/eLife.102230 ↗
  44. 10.1016/j.neuron.2026.01.001 ↗
  45. Collie author-hosted final Neuron PDF ↗
  46. 10.1016/j.cub.2026.06.045 ↗
  47. PubMed record ↗
  48. 10.1101/2025.09.12.675944 ↗
  49. record ↗
  50. Allen announcement ↗
  51. Harvard announcement ↗
  52. Nature collection announcement and exact article list ↗
  53. HMBA portal ↗
  54. NIH budget history ↗
  55. NIH explanatory FAQ ↗
  56. NIH FY2026 final operating plan ↗
  57. funding notices index ↗
  58. 11 March 2025 reporting in The Transmitter ↗
  59. Bader and colleagues, eLife 106136 ↗
  60. Allen human taxonomy ↗
  61. Allen taxonomy catalogue ↗
  62. Schlegel full paper ↗
  63. release notes ↗
  64. first preprint ↗
  65. Citation guidelines ↗
  66. terms ↗
  67. access page ↗
  68. download page ↗
  69. hemibrain official page ↗
  70. Janelia open-science terms ↗
  71. citation policy ↗
  72. Allen terms ↗
  73. MERFISH paper ↗
  74. H01 Released Data, License section ↗
  75. record API ↗
  76. H01 article ↗
  77. Science reuse page ↗
  78. video RQuYaMDc1d0 ↗
  79. 9 April 2025 press page ↗
  80. mesh tutorial ↗
  81. overview ↗
  82. types ↗
  83. visual-motor pathway ↗
  84. Male/female AOTU012 comparison ↗
  85. Harvard 2024 press story ↗
  86. Cambridge University's 45-second FlyWire announcement ↗
  87. https://flywire.ai/tos): ↗
  88. https://flywire.ai/for_media): ↗
  89. https://male-cns.janelia.org/media/): ↗

How this film was made

Created and editorially directed by Anders Lunde using a custom production system developed over six months. AI assists research, drafting, programming, and visual production; I review and edit the material and make the final editorial decisions. Narration uses text-to-speech. Visuals combine custom-built scientific animations, AI-generated reconstructions, and credited scientific imagery.

Generated reconstructions illustrate scientific interpretations. They are distinct from photographs, specimens, and measured data.

More about the creator and production →