Chapter 6 · 13 min
A Brain Changing Through Life
Chapter 6 of How the Brain Works: A Brain Changing Through Life.
How the Brain Works | Ch 6: A Brain Changing Through Life ↗Visual credits
3 sourcesSources and credits for imagery used in this film, including material incorporated into explanatory animations.
Mouse radial glial cell reconstruction, Taverna2016 Figure2A
Elena Taverna, Felipe Mora-Bermudez, Paulina J. Strzyz, Marta Florio, Jaroslav Icha, Christiane Haffner, Caren Norden, Michaela Wilsch-Brauninger, Wieland B. Huttner
View original source ↗Source licence: CC BY4.0Incorporated into an explanatory animation; presentation may include cropping, labels and overlays.
Sleep Hypnogram
RazerM
View original source ↗Source licence: CC BY-SA 3.0Incorporated into an explanatory animation; presentation may include cropping, labels and overlays.
Human brain charts, Figure1
Richard A. I. Bethlehem, Jakob Seidlitz, Simon R. White and coauthors
View original source ↗Source licence: CC BY4.0Incorporated into an explanatory animation; presentation may include cropping, labels and overlays.
Research references
Selected sources from the episode’s research and scientific figures.
- primary DOI ↗
- Wilson/McNaughton PDF ↗
- Staresina 2023 ↗
- Rakic 1972 ↗
- human scaffold study ↗
- Petanjek 2011 ↗
- Hubel/Wiesel 1970 ↗
- PEDIG 2005 ↗
- primary PDF ↗
- NIA ↗
- Seattle analysis ↗
- 2025 perspective ↗
- regional histology ↗
- Dumitru 2025 ↗
- Disouky 2026 ↗
- Xie 2013 ↗
- Miao 2024 ↗
- Hauglund 2025 ↗
- 5:38 SuperAgers film ↗
- research lecture ↗
- Nitramus's hypnogram ↗
- terms ↗
- https://tu-dresden.de/mn/psychologie/allgpsy/ressourcen/dateien/mitarbeiter/ruge-ordner/dat/lehr/rasch2007.pdf ↗
- https://doi.org/10.1016/S0896-6273(02)00746-8 ↗
- https://www.krigolsonteaching.com/uploads/4/3/8/4/43848243/walker_2002.pdf ↗
- https://sc-pan.github.io/pdf/PR_2015.pdf ↗
- https://doi.org/10.1126/science.8036517 ↗
- https://news.mit.edu/1994/rats-0817 ↗
- https://pmc.ncbi.nlm.nih.gov/articles/PMC13059829/ ↗
- https://pmc.ncbi.nlm.nih.gov/articles/PMC12324248/ ↗
- https://www.nichd.nih.gov/health/topics/sleep/conditioninfo/causes ↗
- https://www.nichd.nih.gov/health/topics/sleep/conditioninfo/what-happens ↗
- https://www.nhlbi.nih.gov/health/sleep/stages-of-sleep ↗
- https://www.ninds.nih.gov/sites/default/files/2025-05/understanding-sleep.pdf ↗
- https://doi.org/10.7554/eLife.101992 ↗
- https://pmc.ncbi.nlm.nih.gov/articles/PMC12507438/ ↗
- https://elifesciences.org/articles/101992v1 ↗
- https://www.scienceintheclassroom.org/sites/default/files/research-papers/sleep_drives_metabolite_clearance_from_the_adult_brain.pdf ↗
- https://pmc.ncbi.nlm.nih.gov/articles/PMC11156584/ ↗
- https://pubmed.ncbi.nlm.nih.gov/38741022/ ↗
- https://doi.org/10.1038/s41593-024-01698-0 ↗
- https://doi.org/10.1016/j.cell.2024.11.027 ↗
- https://pmc.ncbi.nlm.nih.gov/articles/PMC12847902/ ↗
- https://www.nature.com/articles/s41593-025-01897-3 ↗
- https://pmc.ncbi.nlm.nih.gov/articles/PMC12340669/ ↗
- https://pmc.ncbi.nlm.nih.gov/articles/PMC5371406/ ↗
- https://doi.org/10.1002/ar.10100 ↗
- https://pmc.ncbi.nlm.nih.gov/articles/PMC10631741/ ↗
- https://www.brainspan.org/static/atlas ↗
- https://www.pnas.org/doi/10.1073/pnas.1105108108 ↗
- https://doi.org/10.1016/0006-8993(79)90349-4 ↗
- https://doi.org/10.1152/jn.1963.26.6.1003 ↗
- https://cw.fel.cvut.cz/b221/_media/courses/a6m33ksy/hubel-wiesel-1964-kittens.pdf ↗
- https://doi.org/10.1152/jn.00061.2008 ↗
- https://doi.org/10.1113/jphysiol.1970.sp009022 ↗
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3528177/ ↗
- https://doi.org/10.1016/j.neuron.2012.03.026 ↗
- https://doi.org/10.1001/archopht.123.4.437 ↗
- https://doi.org/10.1038/s41586-022-04554-y ↗
- https://doi.org/10.1038/s41586-026-10454-2 ↗
- https://pmc.ncbi.nlm.nih.gov/articles/PMC13391363/ ↗
- https://doi.org/10.1038/s41586-026-10693-3 ↗
- https://www.brainchart.io/ ↗
- https://doi.org/10.1038/nature25975 ↗
- https://pmc.ncbi.nlm.nih.gov/articles/PMC6179355/ ↗
- https://pubmed.ncbi.nlm.nih.gov/29625071/ ↗
- https://pmc.ncbi.nlm.nih.gov/articles/PMC5957089/ ↗
- https://doi.org/10.1126/science.adu9575 ↗
- https://news.ki.se/new-research-confirms-that-neurons-form-in-the-adult-brain ↗
- https://doi.org/10.1038/s41586-026-10169-4 ↗
- https://pmc.ncbi.nlm.nih.gov/articles/PMC6800191/ ↗
- https://pmc.ncbi.nlm.nih.gov/articles/PMC4441622/ ↗
- https://d2dg4e62b1gc8m.cloudfront.net/pub_pdfs/HartshorneGermine2015.pdf ↗
- https://sls.psychiatry.uw.edu/about-sls/ ↗
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3607395/ ↗
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3134559/ ↗
- https://doi.org/10.1093/braincomms/fcae412 ↗
- https://pmc.ncbi.nlm.nih.gov/articles/PMC11653079/ ↗
- https://doi.org/10.1016/j.neuron.2024.10.019 ↗
- https://news.northwestern.edu/stories/2025/08/what-makes-a-superager ↗
- https://pmc.ncbi.nlm.nih.gov/articles/PMC4308613/ ↗
- https://pmc.ncbi.nlm.nih.gov/articles/PMC3541673/ ↗
- https://pmc.ncbi.nlm.nih.gov/articles/PMC5801202/ ↗
- https://wellcomecollection.org/works/ckph3npx ↗
- https://www.mncn.csic.es/en/colecciones/documentacion/legado-cajal ↗
- https://journals.physiology.org/permissions ↗
- https://creativecommons.org/licenses/by/4.0/ ↗
- https://alleninstitute.org/legal/citation-policy ↗
- https://www.ninds.nih.gov/publications/publications-help ↗
- https://www.nia.nih.gov/about/policies ↗
- https://www.nia.nih.gov/newsroom/media-frequently-asked-questions ↗
- https://commons.wikimedia.org/wiki/File:Sleep_Hypnogram.svg ↗
- https://www.youtube.com/watch?v=-TH4LjvqnAw: ↗
- https://www.youtube.com/watch?v=ceCnHMUzASQ: ↗
- https://www.youtube.com/watch?v=mAglYDjUWPc ↗
- https://www.youtube.com/watch?v=g5pN8ZRFd4E: ↗
- https://www.youtube.com/watch?v=Nd5UUt7HLUs ↗
- https://www.youtube.com/watch?v=uUvEwg502LU ↗
- https://www.youtube.com/watch?v=Dx8TtHQLQ9g ↗
- https://link.springer.com/article/10.1007/s00429-024-02838-9 ↗
- https://link.springer.com/article/10.1007/s00429-022-02606-7 ↗
How this film was made
Created and editorially directed by Anders Lunde using a custom production system developed over six months. AI assists research, drafting, programming, and visual production; I review and edit the material and make the final editorial decisions. Narration uses text-to-speech. Visuals combine custom-built scientific animations, AI-generated reconstructions, and credited scientific imagery.
Generated reconstructions illustrate scientific interpretations. They are distinct from photographs, specimens, and measured data.
More about the creator and production →